… in vitro data in static or dynamic time–kill curve assays (TKCA) to predict efficacy and the …
of PK/PD principles to predict effective dosages of AMDs in veterinary medicine. Given this …

… effect (eliminating outgrowth from the start of therapy) and killing endpoints have been
evaluated for their predictive value … is most valuable for predicting efficacy in different infection …

… review is to present and discuss the use of pharmacokinetics (… and limit antimicrobial drug
use for therapeutic targeted treat… A critical review of PK/PD in in vitro models,” International …

… in vitro and in vivo infection models, clinical pharmacokinetic … account for the antimicrobial
pharmacokinetics (PK) and … be predicted for different combinations of antimicrobial doses …

… which examine the relationship between drug PK, a measure of in vitro potency (usually the
… of new antimicrobial agents and has been shown to be helpful for predicting efficacy for a …

… activity, and both in vitro and in vivo data have suggested that the free AUC 0–24 /MIC (fAUC
0–24 /MIC) ratio best predicts its activity… of 2 mg/L predicts colistin efficacy whilst limiting the …

… MIC under steady-state pharmacokinetic conditions]) that best predicts bacterial killing, short…
more on nonclinical data to predict successful clinical treatment regimens, often to combat …

… the modern lens of pharmacokinetics/pharmacodynamics (PK… vitro (PD), antimicrobial
exposure to the infecting organism in … is relevant for predicting the therapeutic effect of cephalexin …

… examined pharmacokinetics and pharmacodynamics of antimicrobial … to predict antimicrobial
efficacy are time at which the drug … of the study, the drug concentration in the in vitro time-kill …

… Prediction of outcome based on concentrations in plasma … The antimicrobial activity of
drugs is usually assessed by … (MBC) of the drug under specific conditions in vitro. These in …